How To Treat Calcinosis Cutis

Hematopoietic Stem Cell Transplantation

Hematopoietic stem cell transplantation is a treatment that utilizes allogenic or autologous stem cells to repair a patient's defective or damaged immune system. This is done by matching an appropriate donor to the recipient and then using intravenous means to infuse the patient with stem cells. While calcinosis cutis is not an autoimmune disorder itself, it is closely associated with autoimmune disorders like systemic lupus, dermatomyositis, systemic sclerosis, mixed connective tissue disease, undifferentiated connective tissue disease, rheumatoid arthritis, polymyositis, and overlap connective tissue disease. Hematopoietic stem cell transplantation is an effective treatment for several of these diseases and numerous variants of them. By treating the underlying disease triggering the development of calcium deposits in the skin with hematopoietic stem cell transplantation, the symptoms and outbreaks of calcinosis cutis should significantly decrease in severity and frequency.

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