Side Effects Of Antidepressants

Fatigue

IBDRelief

Fatigue is a common side effect of antidepressants, though the majority of cases tend to resolve after a few weeks of starting the medication. If the fatigue doesn't get better, however, patients should discuss it with their doctor. Like insomnia, fatigue can also be a symptom of the depression itself, which means it's important for patients to make note of their symptoms so they can gauge what is caused by the medication versus their condition.

Tricyclic antidepressants are most likely to cause fatigue, but SSRIs and SNRIs can both also make patients tired. The main goal of antidepressants is to adjust the levels of the neurotransmitters that regulate an individual's mood. However, during this process, the medications can also change other neurotransmitter levels. When acetylcholine and histamine levels are affected, one of the effects is sedation. If patients are so fatigued that staying awake is a struggle, they should speak to their doctor.

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