Common And Serious Side Effects Of Statins

Muscle Inflammation

Although rare, muscle inflammation is a serious side effect that could develop from the use of statins. Patients who take statins along with fibrates are at a higher risk of experiencing this side effect compared to patients who take statins without fibrates or other cholesterol-reducing medication. Rhabdomyolysis, an extreme and potentially life-threatening form of muscle inflammation, has been reported in 0.1 percent of patients who take statins. This condition causes widespread muscle pain and weakness, and it can lead to kidney failure. Patients who notice they suddenly begin having darker urine than normal should contact their healthcare provider immediately. Treatment for rhabdomyolysis typically includes intravenous diuretics such as mannitol, and patients may also need to undergo dialysis.

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