Guide To Kidney Disease Diagnosis And Treatment

Lose Excess Weight

An overweight or obese individual who has been diagnosed with kidney disease may need to lose excess weight to carry out a successful treatment regimen. Excess weight on the body makes an individual more prone to kidney damage through several known and some unknown mechanisms. Several mechanisms that bridge the association between excess weight on the body and kidney disease are factors in comorbid conditions and diseases that promote kidney disease and are caused by being overweight or obese. These comorbid conditions and diseases include diabetes, atherosclerosis, hypertension, and several others. Excess adiposity in an individual's body increases the production of protein hormones like adiponectin, resistin, and leptin. Excess adipose tissues in the body have direct effects on the functionality of the kidneys through the development of oxidative stress, excessive activation of the renin-angiotensin-aldosterone system, insulin resistance, inflammation, abnormal metabolism of lipids, and increased production of insulin. Losing excess weight in the setting of kidney disease can help slow an affected individual's kidney impairment.

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