Causes Of Osteolysis

Abnormal Bone Growth

Bone growths like tumors and cysts, which can be both cancerous or noncancerous, are a part of osteolysis. Some of these growths originate in the bone, while others, namely secondary tumors, start out as malignancies elsewhere in the body and metastasize. The typical locations for primary tumors, whether malignant or benign, are on the distal femur and the proximal tibia. Secondary bone tumors are all metastatic lesions spreading from carcinomas of the breast, prostate, and lungs. Pain is the common symptom of these types of abnormal bone growths, but some individuals may not experience any sign other than a bump or mass. Other symptoms are fever, weight loss, anemia, fatigue, and bones that break for no apparent reason. Sometimes bones break with osteolysis because the abnormal growth makes the adjacent bones weaker.

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