Warning Signs Linked To A Vitamin E Deficiency

General Malaise

General malaise can be best described as a feeling of unwellness and fatigue. This symptom occurs as the result of hemolytic anemia precipitated from vitamin E deficiency. An increase in erythrocyte fragility is implicated in the development of anemia in affected individuals. Erythrocyte fragility refers to a decreased ability of the red blood cells to resist breakdown when under stress, causing the red blood cells to become extremely vulnerable to destruction in states of oxidative stress. The faster and easier destruction of red blood cells due to the absence of vitamin E can cause a decrease in a patient's red blood cell count. Low numbers of functioning red blood cells cause an inability to sufficiently carry and deliver oxygen to all of the tissues in the body. This mechanism causes the affected individual to feel malaise, fatigue, and weakness.

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