Symptoms Of Primary Biliary Cholangitis

Fatty Deposits Around The Body

Fatty deposits around the body can be a symptom indicative of primary biliary cholangitis. As the bile ducts become damaged due to inflammation, the secretions of bile into the intestines decrease. Because lipids or fats are secreted in bile as bile acids, individuals with less bile secretion all together tend to have high levels of serum cholesterol. Additionally, lipoprotein X or LpX is found in individuals affected by primary biliary cholangitis. Lipoprotein X is an abnormal lipoprotein that causes blood cholesterol levels to stay elevated due to its inability to be synthesized properly. The high cholesterol levels in the blood can result in it depositing in the form of fatty yellow-colored lumps around the body. These deposits commonly occur on the lower and upper eyelids, around both eyes, and near the inner corner of the eyes. The deposits themselves are not particularly harmful but can cause discomfort in affected individuals. Fatty deposits from primary biliary cholangitis can be surgically removed for aesthetic and symptomatic purposes but will grow back if the cholesterol levels remain elevated in the patient's blood.

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