Causes Of Orthostatic Intolerance

Extended Bedrest

Long periods of lying down cause the body to adjust to this new normal. Changes in the muscular, neurological, and cardiovascular systems adjust to the minimal activity and body's reclined position. The hormonal and chemical makeup in the body, which helps control blood pressure and heart rate, begins to adjust as well. After just one day in bed, the fluid in the body's tissue begins to shift into the blood vessels, and hormones begin to release salt and water through increased urine. As a result, blood volume reduces to a new normal, and there is less blood flowing throughout the body to distribute oxygen and nourish the organs, tissue, and muscles. Upon standing, the body needs to readjust to the new upright position, but may have difficulty with less blood flow.

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