Signs Of Hypophosphatasia

Osteomalacia

Osteomalacia is the softening of bones and is one of the major signs of hypophosphatasia in adults. It is caused by the inadequate absorption of vitamin D, phosphate, and calcium in the bones. Consequently, they become soft, which can lead to broken bones, muscle weakness, fatigue, stiffness, and pain. It may be painful for a person to move from a seated position or to climb and descend stairs. They may have difficulty performing daily chores and activities. Individuals suffering from this may benefit from wearing braces to support the weakened bones. Adding vitamin D, calcium, and phosphate supplements will likely not help and can aggravate the condition.