Signs Of Hypophosphatasia

Early Loss Of Baby Teeth

The early loss of baby teeth is a sign of a less severe form of hypophosphatasia. In fact, it might be the first noticeable sign of the disease in young children. Normally, baby teeth fall out slowly when children are between six and twelve years old. A child with hypophosphatasia will have lost all baby teeth, including the root, by five years old. This is often caused by the weakening of the ligaments that hold them in place, and by their fragile bones. Early loss of the primary teeth can be troublesome for the placement of the permanent teeth. When primary teeth are lost gradually and individually, the adult teeth behind them have a guide to follow into their permanent place. Without this guide, adult teeth can grow into any open spaces.

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