Common Indicators Of McLeod Syndrome

Peripheral Neuropathy

Most individuals affected by McLeod syndrome develop some degree of peripheral neuropathy. Peripheral neuropathy is an umbrella term encompassing a range of conditions that happen when certain nerves in an individual's body are damaged or diseased. These nerves include those that transmit signals from the rest of the body to the spinal cord and brain, as well as those that transmit signals from the brain and spinal cord back to the rest of the body. The peripheral nerves create a complex network that attaches the spinal cord and brain to the internal organs, muscles, and skin. The most common manifestations of peripheral neuropathy in McLeod syndrome patients are feelings of numbness, tingling, loss of sensation in arms and legs, and a burning sensation in the hands or feet. This type of neuropathy can have adverse effects on the nerves that control the movement of muscles or the motor nerves as well as the sensory nerves or the nerves responsible for detecting sensations of pain and temperature changes.

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