What Causes Dystonia?

Wilson's Disease

Wilson's disease is a genetic condition that causes the body to accumulate an excessive amount of copper. The copper builds up in the liver and brain, and it can cause neurological symptoms. Patients may experience tremors, stiff muscles, uncontrollable movements, and problems with physical coordination. They may have difficulty with swallowing, speech, and walking. Most patients usually find the severity of these symptoms is reduced with proper treatment for Wilson's disease. Chelating agents enable the body to release excess copper through the urine. Penicillamine and trientine are two examples of these drugs, and they are normally taken as the first treatment for this illness. Since these medicines can make neurological symptoms worse, patients will need careful monitoring during treatment. After copper levels have been reduced, most patients are placed on maintenance therapy with zinc acetate, which blocks the body's ability to absorb copper from food and helps patients keep their copper levels within a normal range. Zinc acetate does not cause or worsen neurological symptoms.

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