Causes And Complications Of Wilson's Disease

Neurological Issues

Patients with Wilson's disease may experience a variety of neurological issues. For example, lack of coordination, gait abnormalities, tremors, and slurred speech could occur. Some individuals might experience involuntary muscle movements or twitching, and speech difficulties have been observed. For some patients, neurological issues could be accompanied by psychological changes such as depression, irritability, mood swings, and changes in personality. Bipolar disorder and episodes of psychosis may develop. These neurological and psychological changes typically improve or resolve with appropriate treatment for Wilson's disease, although some patients may have lingering neurological difficulties even with treatment. To assess neurological issues, clinicians will check the patient's gross and fine motor skills and check for any signs of involuntary muscle movements. If present, psychological changes can be addressed with a mental health specialist. In addition to medications for Wilson's disease, patients may benefit from other medicines that could reduce tremors and muscle twitching. Medications for mental health concerns might be useful as well.