Treatments For Squamous Cell Carcinoma

Medicated Creams

Some skin cancers can be treated by applying medicated creams directly onto the diseased area of skin. These creams are topical treatments and they usually contain drugs used for cancer therapy. 5-fluorouracil (5-FU) and imiquimod creams are used to treat early forms of SCC called squamous cell carcinoma in situ, Bowen disease, or actinic keratoses. Imiquimod triggers the immune system to produce an anticancer chemical, while 5-FU is a form of chemotherapy. Both creams are FDA-approved and are being tested for effectiveness in treating other superficial squamous cell carcinomas. Imiquimod use may cause inflammation and tenderness. Side effects include pain, itching, fever, or achy joints. Patients should contact their healthcare provider if they're experiencing side effects from usage. 5-FU can also cause effects such as blistering or redness, but they are usually temporary and minor. Patients should avoid the sun while using 5-FU because the treated skin will be more sensitive to the sun's effects. Certain invasive forms of SCC may be treated with imiquimod in the future, but trials are still being conducted to prove its effectiveness.