Guide To Bone Cancer Causes And Risk Factors

Osteochondroma And Chondroma

Individuals affected by either osteochondroma or chondroma are at an increased risk of developing cancer in their bone tissue. Multiple osteochondromas syndrome is a hereditary condition that produces numerous bumps on a patient's bone. These growths are formed out of abnormal cartilage and can cause the patient to experience fractures and deformities in their bones. This syndrome occurs as a result of a mutation in the EXT1, EXT3, or EXT2 gene. Multiple osteochondromas syndrome puts a patient at an increased risk of developing a form of bone cancer called chondrosarcoma. Chondroma describes a noncancerous tumor on the bone that develops from cartilaginous material. Chondromas occur most commonly on the small bones of an individual's feet and hands, but can also develop in their ribs, humerus, and femur. An individual affected by one or more chondromas is at an increased risk of developing bone cancer because there is more growth that provides a better opportunity for a cancer-causing mutation to occur.

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