What Causes Neutrophilia?
Certain Forms Of Leukemia
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An individual's neutrophilia can be caused by certain forms of leukemia or blood malignancies. Chronic myeloid leukemia is a malignancy that begins in an affected individual's bone marrow or blood-forming tissues. In the beginning stages of this type of leukemia, the bone marrow produces an excess amount of white blood cells. However, myeloblasts or immature white blood cells begin to accumulate in the patient's bone marrow and blood, resulting in a decrease of red blood cell and platelet production. Acute myeloid leukemia also causes neutrophilia, but on a much quicker timeline than its chronic form. Myelofibrosis is a chronic form of leukemia where an affected individual's bone marrow is replaced by scar tissue. This results in an excess of red and white blood cells that do not fully mature and cannot function as healthy cells. Chronic neutrophilic leukemia is a slow-growing malignancy of the bone marrow where it makes too many neutrophils, a specific type of white blood cell. Acute neutrophilic leukemia also causes neutrophilia but grows at a much faster rate.
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