Guide To The Symptoms Of Cowden Syndrome

Cowden syndrome is a genetic condition where an individual develops numerous hamartomas or noncancerous growths on multiple parts of their body and are at an increased risk for certain types of cancer. Cowden syndrome is the result of one or more PTEN tumor suppressor gene mutations in most cases. Mutations in genes that supply the code for producing certain proteins result in the formation of the hamartomas and higher vulnerability to certain cancers in Cowden syndrome. One or more mutations in the KLLN, SDHC, PIK3CA, SDHB, SDHD, and AKT1 genes can also cause Cowden syndrome.