Treatments For Alagille Syndrome

Alagille syndrome is an inherited disorder that can affect many parts of the body, including the liver and heart. One of the most prominent features of the disorder is damage to the liver due to abnormalities in the bile ducts. Bile plays a vital role in digesting fat, and the ducts remove it from the liver, carrying the bile to the gallbladder and small intestine. Individuals with this syndrome may possess fewer ducts than the average person. Alagille syndrome can affect individuals in a variety of ways, differing from person to person. It can even present differently in individuals within the same family. Mild forms of the condition may not even be noticed until adulthood, while others can be diagnosed as babies. Possible symptoms include blood vessel and heart problems, abnormalities with the eyes, and distinctly abnormal facial features and skeletal shape. Patients may also exhibit jaundice, excrete pale feces, experience prevalent nose bleeds and bleeding gum, have trouble absorbing nutrients, and even be afflicted by cirrhosis.